Co-host of the All-In podcast and a serial founder, including The Climate Corporation. Focuses on science, agriculture and deep tech.
Freeberg argues Apple's clearest AI win is acquiring a frontier lab (Perplexity/Mistral) and running local models on its new M5/Mac Studio hardware (48GB-1TB RAM), solving privacy and persistence via iCloud. He calls Apple his "choice for the next year."
The neoantigen immunotherapy process — sequencing a tumor, identifying unique mutations, delivering matching antigens via mRNA or peptide — was developed over decades with NIH funding and can be executed for ~$50K; Moderna's $500K price and patent strategy represent regulatory capture, not innovation.
With the US government fiscally constrained by debt, private companies like Nvidia, Google, Microsoft, Meta and Amazon are effectively putting the entire AI infrastructure buildout on their balance sheets — a role historically played by the federal government.