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max hodak

T2 · manager / operator

Max Hodak is the founder of Science, a brain-computer interface company developing the Prima retinal prosthesis (restoring form vision in clinical trials), bio-hybrid neural interfaces, and portable perfusion technology. He co-founded Neuralink in 2016 after an email from Sam Altman connected him with Elon Musk. Previously founded Transcriptic, a robotic cloud laboratory. Holds a biomedical engineering degree and has worked on primate BCI research since 2008.

13 calls·8 names·92% bull·last heard 2 months ago·Y Combinator+1
track record

no scored calls yet — needs a stated position or a categorical verdict, with a matured window vs SPY

top calls

highest conviction · one per company
1sthigh conviction
$SCIENCEScienceposition

Science CEO details retinal prosthesis clinical success and internal OS

Science's retinal implant has completed major clinical trials with patients achieving functional vision like reading novels, powered by proprietary internal software Helix that integrates procurement, manufacturing, and quality systems.

Y Combinator2026-08episode →
2ndmedium conviction
$SCIENCE-CORPORATIONScience Corporationposition

Science Corp's retinal implant gets EU approval, FDA pathway underway for blindness cure

Science Corporation's Prima retinal prosthesis received CE mark for 30 European countries with first patient implants in 6 weeks, plus FDA humanitarian use designation enabling expedited US review, commercializing a 1-hour outpatient procedure that restores functional vision to AMD patients.

TBPN2026-07episode →
3rdmedium conviction
$Y-COMBINATORY Combinator

Internal software drives Y Combinator's effectiveness

Y Combinator’s internal software streamlines its applicant‑tracking and partner‑selection processes, reducing friction and letting the firm scale its accelerator model more efficiently than if it relied on generic tools.

Y Combinator2026-08episode →

most discussed · click a bar to filter

  • $SCIENCE
  • $Y-COMBINATOR
  • $SPCX
  • $META
  • $TSLA

recurring themes

  • Brain-Computer Interfaces3
  • AI Infrastructure3
  • AI Drug Discovery2
  • AI in Healthcare2
  • Longevity & Aging2
13 total
$Y-COMBINATOR
Y Combinator
MEDmax hodak·Y Combinator·2 months ago·Max Hodak: “Speed Is Determined by Infrastructure”
Internal software drives Y Combinator's effectiveness
Y Combinator’s internal software streamlines its applicant‑tracking and partner‑selection processes, reducing friction and letting the firm scale its accelerator model more efficiently than if it relied on generic tools.
"YC famously has a lot of internal software that I think really makes YC work."
38:09
$SPCX
···
SpaceX
MEDmax hodak·Y Combinator·2 months ago·Max Hodak: “Speed Is Determined by Infrastructure”
Internal software gives SpaceX a manufacturing edge
SpaceX’s internal Warp Speed software ties together manufacturing and R&D steps, removing delays from vendor negotiations and paperwork. This lets the firm iterate on hardware far quicker than competitors using generic ERP or PLM systems.
"SpaceX and Tesla internally have a pretty giant piece of software called Warp Speed that runs a lot of their manufacturing and R&D processes. And so when one company grows up arou…"
38:21
$META
···
Meta
MEDmax hodak·Y Combinator·2 months ago·Max Hodak: “Speed Is Determined by Infrastructure”
Internal tools boost Meta's efficiency
Meta’s investment in internal tools automates and streamlines internal workflows, cutting out inefficiencies from third‑party software and letting teams move faster on product development.
"Facebook also very famously invested heavily in internal tools and now has um like I think gets a lot of efficiency from that."
38:11
$TSLA
···
Tesla
MEDmax hodak·Y Combinator·2 months ago·Max Hodak: “Speed Is Determined by Infrastructure”
Internal software gives Tesla a manufacturing edge
Tesla’s internal Warp Speed software integrates manufacturing and R&D processes, removing delays from vendor negotiations and paperwork, which lets the firm iterate on hardware far quicker than competitors using generic ERP or PLM systems.
"SpaceX and Tesla internally have a pretty giant piece of software called Warp Speed that runs a lot of their manufacturing and R&D processes. And so when one company grows up arou…"
38:21
$SCIENCE
Science
HIGHmax hodak·Y Combinator·2 months ago·Max Hodak: “Speed Is Determined by Infrastructure”· position
Science CEO details retinal prosthesis clinical success and internal OS
Science's retinal implant has completed major clinical trials with patients achieving functional vision like reading novels, powered by proprietary internal software Helix that integrates procurement, manufacturing, and quality systems.
"At our company science our main product is a retinal prostthesis. It's a chip that's implanted under the retina in the back of the eye to restore vision to patients that have gone…"
0:45
$META
···
Meta Platforms
MEDmax hodak·Y Combinator·2 months ago·Max Hodak: “Speed Is Determined by Infrastructure”
Meta's heavy internal tools investment yields significant efficiency gains
Meta's famous investment in custom internal software has created substantial operational efficiency, serving as a model for deep tech companies building their own infrastructure.
"Facebook also very famously invested heavily in internal tools and now has um like I think gets a lot of efficiency from that."
38:13
$Y-COMBINATOR
Y Combinator
MEDmax hodak·Y Combinator·2 months ago·Max Hodak: “Speed Is Determined by Infrastructure”
Y Combinator's internal software is core to its operational effectiveness
Y Combinator's custom-built internal software platform is a key enabler of its accelerator operations, demonstrating the value of bespoke tools for organizational workflows.
"YC famously has a lot of internal software that I think really makes YC work."
38:09
$GREENHOUSE
Greenhouse Software
MEDmax hodak·Y Combinator·2 months ago·Max Hodak: “Speed Is Determined by Infrastructure”
Greenhouse ATS replaced due to bottlenecking hiring funnel at Science
Greenhouse's applicant tracking system forced a small team bottleneck at the top of the hiring funnel, prompting Science to build custom voting-based hiring software that distributes review across the company.
"we previously had used a we used greenhouse. Um greenhouse required us to have a small number of people as a bottleneck at that at that first funnel stage. Um replacing that with…"
39:01
$SPCX
···
SpaceX
MEDmax hodak·Y Combinator·2 months ago·Max Hodak: “Speed Is Determined by Infrastructure”
SpaceX's Warp Speed internal software exemplifies custom infrastructure advantage
SpaceX's custom manufacturing and R&D software Warp Speed demonstrates how companies growing up around bespoke internal tools gain powerful operational efficiency that off-the-shelf software cannot provide.
"SpaceX and Tesla internally have a pretty giant piece of software called Warp Speed that runs a lot of their manufacturing and R&D processes. And so when one company grows up arou…"
38:20
$SCIENCE
Science
HIGHmax hodak·Y Combinator·7 months ago·The Future Of Brain-Computer Interfaces· position
Science's Prima retinal prosthesis restores form vision in clinical trial, submitting for approval
Science's subretinal implant stimulates bipolar cells (not compressed ganglion cells), enabling coherent form vision — first ever in a clinical trial — with 40+ patients treated and NEJM publication; path to near-normal 20/20 vision in 10 years.
"So it's a little chip, a tiny little 2 mm by 2 mm silicon chip that's implanted in the back of the eye under the retina that is a tiny little array of essentially solar panels...…"
0:51
9
Brain-Computer Interfacestailwind
BCI is a category like pharma — multiple modalities for distinct applications, not a single product
Different BCI modalities (retinal implants, cortical threads, ultrasound, bio-hybrid) will serve different indications: vision restoration, motor decoding, neuromodulation (focus/sleep), and eventually high-bandwidth brain-to-brain interfaces; bio-hybrid only needed for highest-end applications, electrical stimulation scales faster for near-term medical needs.
9
Brain-Computer Interfacestailwind
BCI is a longevity healthcare story with unprecedented effect sizes, not just AI adjacency
Neural engineering directly interfaces with the brain as a computer, bypassing intractable biology problems to deliver large, reliable therapeutic effects like restoring vision or motor function, making it a radical longevity play rather than merely an AI story.
9
Brain-Computer Interfacestailwind
BCI is a longevity story with larger effect sizes than pharma
Hodak frames neural engineering as a healthcare/longevity play rather than AI-adjacent, arguing that direct neural stimulation produces dramatic clinical effects (e.g., DBS enabling cursive writing in seconds) that dwarf traditional pharmacology.
8
AI Drug Discoverytailwind
Neural engineering outperforms drug discovery for sensory/motor restoration — bypasses molecular heterogeneity
Drug discovery fails for complex degenerative diseases (e.g., blindness) because each molecular etiology differs and trials take a decade with high failure rates; neural engineering substitutes hardware for biology — one retinal prosthesis works across AMD, retinitis pigmentosa, Stargardt's because it replaces the photoreceptor layer's computational role regardless of cause.
8
AI Infrastructuretailwind
AI and neuroscience representations converging — latent spaces in models mirror brain's object manifolds
Deep unification underway: representations in trained vision/language models structurally resemble neural population codes in inferotemporal cortex and other areas; neuroscience increasingly uses AI models as tractable proxies, accelerating BCI decoding and neural engineering.
8
Startup Strategytailwind
Fast iteration loops beat slower rivals through compounding learning
Startups that can iterate quickly compound knowledge faster than slower competitors, making speed the decisive factor. This speed is enabled by robust internal infrastructure such as streamlined purchasing, recruiting, and performance‑review systems.
8
AI Infrastructuretailwind
Custom internal software (Helix, Warp Speed) is the operating system that determines company speed and success
Speed of iteration separates startup success from failure, and speed is determined by boring infrastructure like purchasing, hiring, and performance review systems; building bespoke tools like Science's Helix or SpaceX's Warp Speed creates compounding advantages that generic ERP/ATS cannot.
8
AI in Healthcaretailwind
AI agents transform regulatory compliance from bottleneck to speed
Quality system compliance — historically a months-long manual process of mapping standards to evidence — is now accelerated by AI agents that can rapidly identify applicable standards and generate evidence tables, turning regulatory burden into a tractable software problem.