jack dent

T2 · manager / operator

Co-founder of Chai Discovery, a full-stack AI drug discovery company building 3D atomic models for molecule design. Raised $400M at $3.8B valuation from Index, Kleiner Perkins, Sequoia, Dimension. Models deployed in discovery programs at Eli Lilly, Novartis, Pfizer.

1 call·1 name·100% bull·last heard 28 days ago·TBPN
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$CHAI-DISCOVERYChai Discoveryposition

Chai Discovery raises $400M at $3.8B to deploy atomic-level AI drug design at pharma giants

Chai's 3D atomic models crossed the Rubicon in 2025, moving from 0.1% success rates to zero-shot antibody design deployed in real discovery programs at Eli Lilly, Novartis, and Pfizer. The company builds custom architectures (not fine-tuned LLMs) trained on protein sequencing/structure data and in-house generation, creating a full-stack platform where scientists can prompt targets and receive binders — solving in hours what took careers.

TBPN2026-07

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$CHAI-DISCOVERY
Chai Discovery
HIGHjack dent·TBPN·28 days ago· position
Chai Discovery raises $400M at $3.8B to deploy atomic-level AI drug design at pharma giants
Chai's 3D atomic models crossed the Rubicon in 2025, moving from 0.1% success rates to zero-shot antibody design deployed in real discovery programs at Eli Lilly, Novartis, and Pfizer. The company builds custom architectures (not fine-tuned LLMs) trained on protein sequencing/structure data and in-house generation, creating a full-stack platform where scientists can prompt targets and receive binders — solving in hours what took careers.
"In 2025 we really like crossed the Rubicon in a way... these technologies are are you know be actively being deployed in companies like Eli Liy Novatist FISA... making them part o…"
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