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▶ 44:16 · AI in Healthcare · Digital therapeutics face broken economics: high FDA/payer barriers with low IP defensibility
episode briefing
The Logan Bartlett Show

General Medicine's Elliot Cohen on Lessons from PillPack & Amazon and The Future of AI x Healthcare

2025-07-31 · 3 company · 5 thematic
sentiment
2 bull0 bear1 neu
speakers
elliot cohen
now playing · AI in Healthcare
Healthcare Systems & Policytailwindscore 9/10elliot cohen
Removing employers as healthcare purchasers would align system incentives with consumers
Almost all healthcare dysfunction stems from the consumer not being the customer. Employers create churn and misaligned incentives; shifting to consumer-directed purchasing (like AT&T phone…
Healthcare Systems & Policytailwindscore 8/10elliot cohen
Eliminating rebates is the single highest-impact lever to fix drug price transparency
Rebates (40-50% of list price) destroy price signals for consumers and providers. Removing them would restore genuine price competition between drugs. PBMs currently optimize for payer (emp…
AI in Healthcaretailwindscore 8/10elliot cohen
AI is a magical co-pilot for clinicians and consumers, not a replacement for doctors
Current LLMs are exceptional at synthesizing patient history, preparing visits, and stringing together operational follow-ups (prior auths, referrals, prescriptions), but are far from repla…
AI in Healthcareheadwindscore 8/10elliot cohen
Digital therapeutics face broken economics: high FDA/payer barriers with low IP defensibility
DTx require drug-level clinical trials and payer reimbursement but lack patent protection (easy to copy), creating a go-to-market trap. Most would be better served as direct-to-consumer cas…
Healthcare Systems & Policymixedscore 7/10elliot cohen
Policy debate focuses on patent extensions instead of accelerating breakthrough drug creation
Society should worry far more about the next Hepatitis C cure (which dropped from $100k to $15k in 6 months) not being invented than about Humira's patent thicket. The learning curve for bi…