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▶ 30:15 · AI Infrastructure · KV cache inefficiency demands new training infrastructure for personalized models
episode briefing
Sequoia Capital

Memory and Continual Learning: Engram's Dan Biderman and Jessy Lin

2026-06-24 · 1 company · 3 thematic
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dan biderman

Neuroscience PhD from Stanford, former researcher at MosaicML, co-founded Engram to solve memory and continual learning for enterprise AI through adapter-based continual training.

now playing · AI Infrastructure
Memory & Storagetailwindscore 8/10dan biderman
Continual learning via weight updates beats RAG for enterprise AI adoption
Externalized memory (RAG/context engineering) hits scaling limits with token costs and retrieval failures, while training adapters on private data enables 100x inference reduction and impli…
Enterprise AI Adoptiontailwindscore 7/10jessy lin
Frontier labs' AGI focus leaves enterprise continual learning underserved
Frontier labs prioritize generic AGI capabilities (coding/math) with clean supervision, while enterprise needs involve ambiguous, private, conflicting preferences that require integrated re…
AI Infrastructuretailwindscore 7/10dan biderman
KV cache inefficiency demands new training infrastructure for personalized models
KV caches for long contexts consume massive HBM (80GB for a single Wikipedia article vs 100GB for entire Llama-70B weights), proving current inference architecture is bit-inefficient. Offli…